The FDA’s Center for Drug Evaluation and Research (CDER) regulatory approval of a total of 26 NME (New Molecular Entity) drugs in the first half of 2023. It is worth noting that the 26 drugs approved include 4 peptide drugs, accounting for 15% of the total. In the past 2022, the FDA has approved only…
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In recent years, nucleic acid therapy involving various types of ribonucleic acids (RNAs), including messenger RNA (mRNA), small interfering RNA (siRNA), and microRNA (miRNA), has rapidly emerged as a new cornerstone of modern medicine. Among them, the mRNA-based vaccines developed, particularly the COVID-19 vaccine, have played a significant role in combating the novel coronavirus (SARS-CoV-2)…
Antibody-drug conjugates (ADCs) have revolutionized the field of targeted cancer therapy by combining the specificity of monoclonal antibodies with the potency of cytotoxic drugs. ADCs have shown remarkable clinical success, leading to several FDA-approved therapies. However, the development of the next generation of ADCs presents new strategies and challenges that must be addressed to improve efficacy,…
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Antibody-drug conjugates (ADCs), as emerging anticancer drugs, can deliver highly cytotoxic molecules directly to cancer cells to kill them. ADC is a monoclonal antibody covalently bound to cytotoxic chemical substances (payload) through linker. ADC linker plays a key role in the therapeutic effect of ADC, and its characteristics greatly affect the therapeutic index, pharmacodynamics and pharmacokinetics…
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Targeted therapies have significantly advanced the field of cancer therapy, and among these, antibody-drug conjugates (ADCs) have emerged as a viable therapeutic strategy. ADCs increase efficacy and decrease systemic toxicity by fusing the potency of cytotoxic drugs with the specificity of monoclonal antibodies (mAbs). The manufacture of high-quality and stable payloads by fermentation techniques is…
With the rise of wireless connectivity, printers have embraced the convenience of connecting to WiFi networks, making printing tasks more flexible and efficient.
Peacocktv.com/tv is a streaming service launched by NBCUniversal, a subsidiary of Comcast Corporation. It offers a wide variety of television shows, movies, original content, live sports, news, and more. Peacocktv.com/tv is designed to provide viewers with on-demand access to a broad range of entertainment options, both from NBCUniversal’s extensive library and new, exclusive content produced specifically for the platform.
In this technologically advanced era, finding and retaining top-notch talent has become a significant challenge for organizations. As competition increases and skill gaps widen, companies are exploring innovative ways to access the best candidates to improve their growth. One strategy that has gained substantial power is the utilization of offshore recruitment services. These services offer…
